<p>Calpol 650 Plus Tablet contains Paracetamol, an analgesic (pain killer) and antipyretic (reduces fever). It inhibits the production of certain chemical messengers in the brain known as prostaglandins, reducing pain. Also, Calpol 650 Plus Tablet affects an area of the brain that regulates body temperature known as the hypothalamic heat-regulating centre, reducing fever.</p>